microbiology

1. Frameshift, because it will scramble everything after it.

2. Introns r parts of the mRNA that do not get translated into proteins. Exons get translated.

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DNA polymerase is a multi-subunit enzyme that strings deoxyribonucleotides together to make DNA.

Okazaki fragments: DNA synthesis occurs 5' to 3' always. However, as the polymerase is going down the DNA away from the origin of replication, one strand runs one way & one runs the other. This means that one strand has to be synthesized in small chunks running backwards, using bits or RNA as primers. These chunks r called okazaki fragments, & they will later be joined together to make one continuous piece of DNA.

Check out the source below. I am tired & possibly not explaining things well, but below is a short simple web page summary that I think all ur questions:

A point mutation is a change in a single amino acid. When a frameshift occurs, then the reading frame changes & most amino acids after the shift r changed. So, which would be more detrimental - one change or many changes

Exons r the part of the gene that r expressed, that is read into amino acids to make protein. Introns r the intervening sequences that r not read into amino acids

DNA replication is when DNA is copied, to make 2 strands from 1 strand. This is done by a DNA polymerase

For rest, see:

http://en.wikipedia.org/wiki/DNA_replication